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There are various types of vaccines based on the type of antigen. The production of vaccines is a complex process that involves many steps and procedures. Cobetter single-use technologies and filtration products play an important role in the production of traditional vaccines, virus vector vaccines and recombinant vaccines.
Vaccine Type
Virus-Based Vaccines
Virus-based vaccines include attenuated vaccines and inactivated vaccines. Attenuated virus-based vaccines are biologically active vaccines that reduce their virulence through multiple generations of reproduction, and their protective effects can last for several years. Inactivated virus-based vaccine refers to a non virulent vaccine that injects non replicating antigens of virus into the human body to elicit an immune response and produce antibodies, making it relatively safe.
Viral Vector Vaccines
Viral vector vaccines are a new type of vaccine. It involves loading nucleic acid fragments of the virus onto a safe viral vector (such as Adenovirus) and then injecting them into the human body. The human immune system recognizes the antigen and activates out immune response to obtain immunity.
mRNA Vaccines
COVID-19 brought unprecedented pressure to drug developers. mRNA vaccine adopts a non-viral delivery system, and can be manufactured in a cell-free system, offering rapid, economical and efficient production.
Recombinant Protein Vaccines
Recombinant protein vaccines, also called protein subunit vaccines, using purified recombinant viral protein fragments as antigens, transforming them into bacterial, yeast, mammalian or insect cells to stimulate the immune system and produce protective immunity. As the viral protein fragments are not able to cause infection, recombinant protein vaccines are considered to be safer and more stable than attenuated or inactivated vaccines.
Viral Vector Vaccines Process Workflow
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TFF Cassettes
Available in PES and RC ultrafiltration membrane, with a wide range of MWCO. Low protein binding, easy linear scale-up from lab to process and production.Learn More -
Roheap CSD Lenticular Depth Filter
Adopts advanced and highly automated production process, and all raw materials undergo strict quality control procedures to ensure uniform product quality and filtration performance.Learn More -
Purcise PLE Prefilter
Unique two layer design with hydrophilic PES membrane. Reliable bacteria and particle retention ability. Used for buffer filtration and column protection.Learn More -
Purcise? Q Membrane Adsorber Capsule
A strong anion exchange membrane chromatography adsorber, with high-throughput and high binding capacity, designed for biomolecule purification. Ready to use.Learn More -
Purcise SLE Sterilizing-grade Filters
Made of PES membrane, low adsorption and low extractables, withstand dry sterilization. SLE filter is the preferred choice for final sterile filtration.Learn More
